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October 1, 1999Pediatrics International

Autonomic nervous system function in childhood migraine

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Why the study?

Do children with migraine have autonomic nervous system dysfunction compared to healthy controls?

Population

55 children, consisting of 25 with migraine and 30 healthy controls

Comparison

Childhood migraine (exposure) vs Healthy children

Design

Case-control

Authors

CYCengiz YakıncıInonu UniversityBMBülent MungenSema HospitalHEHamdi ErUniversity of Southern California

Discussion

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Implication

Supports autonomic hyperactivity in pediatric migraine; hypothesis-generating and should not yet change practice.

Structured PICO

Do children with migraine have autonomic nervous system dysfunction compared to healthy controls?

P
Population
55 children, consisting of 25 with migraine and 30 healthy controls
I
Intervention
Childhood migraine (exposure)
C
Comparator
Healthy children
O
Outcome
Autonomic nervous system function (measured by orthostatic test, sustained handgrip, Valsalva ratio, 30/15 ratio, and heart rate responses to deep breathing)surrogate

Children with migraine exhibit autonomic nervous system dysfunction characterized by both sympathetic and parasympathetic hyperactivity.

Cite This Study

Yakıncı et al. (1999) studied this question.

synapsesocial.com/papers/6a7266628031ec7bb1dd598ahttps://doi.org/10.1046/j.1442-200x.1999.01101.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Autonomic Dysfunction in Adult Migraineurs1986 · 54 citations
  2. 2Autonomic Dysfunction in Migraine: A Survey of 188 Patients1988 · 59 citations
  3. 3Autonomic Function Testing in Patients with Migraine1993 · 81 citations
  4. 4Cardiovascular Reflexes in Young Migraine Patients1986 · 20 citations
  5. 5Autonomic Nervous System Function in Migraine Without Aura1991 · 60 citations