Key result
The percentage decrease in parasympathetic activity (RR-HF) at 40 seconds after head-up tilting was the primary determinant of maximum systolic blood pressure fall (r=0.56, p=0.004).
Why the study?
Does instantaneous autonomic regulation impairment relate to blood pressure fall immediately after standing in elderly and hypertensive subjects?
Population
32 subjects (15 hypertensive and 17 normotensive subjects)
Comparison
Head-up tilt test with continuous… vs Normotensive subjects and non-elderly subjects
Design
Cross-sectional
Follow-up
2 minutes
Authors
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May link delayed parasympathetic withdrawal to orthostatic BP fall in elderly hypertensives; hypothesis-generating, needs prospective confirmation.
Cross-Sectional (n=32)
No
Does instantaneous autonomic regulation impairment relate to blood pressure fall immediately after standing in elderly and hypertensive subjects?
Effect estimate: r=0.56
p-value: p=0.004
Delayed autonomic regulation, as measured by real-time wavelet transformation, is a major confounding factor for blood pressure fall immediately after standing in hypertensive and elderly subjects.
Moriguchi et al. (2006) conducted a cross-sectional in Hypertension and orthostatic hypotension (n=32). Head-up tilt test vs. Supine position was evaluated on Determinants of maximum systolic blood pressure fall during 120 seconds following head-up tilt (r=0.56, p=0.004). The percentage decrease in parasympathetic activity (RR-HF) at 40 seconds after head-up tilting was the primary determinant of maximum systolic blood pressure fall (r=0.56, p=0.004).
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