Key result
Intravenous amiodarone predictably reduces ventricular rate after 300-400 mg, while restoration of sinus rhythm may require 24 hours and doses of 1,000 mg or more.
Why the study?
Does intravenous amiodarone improve rate control and rhythm control in patients with atrial fibrillation?
Population
Patients with atrial fibrillation, generally in the intensive care unit setting and most often after cardiac…
Design
Review
Authors
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Supports IV amiodarone for AF rate control; leaves open its role in cardioversion and prophylaxis.
Does intravenous amiodarone improve rate control and rhythm control in patients with atrial fibrillation?
Intravenous amiodarone is effective for ventricular rate reduction in atrial fibrillation, but its role in cardioversion and prophylaxis requires further study.
James A. Reiffel (1999) conducted a review in Atrial fibrillation. Intravenous amiodarone was evaluated. Intravenous amiodarone predictably reduces ventricular rate after 300-400 mg, while restoration of sinus rhythm may require 24 hours and doses of 1,000 mg or more.
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