Why the study?
Does slow intravenous amiodarone restore sinus rhythm and improve hemodynamics in critically ill patients with acute atrial fibrillation or flutter and severely depressed left ventricular function (LVEF < 15%)?
Population
8 critically ill, invasively monitored patients with acute onset of atrial fibrillation or atrial flutter…
Design
Case_series
Follow-up
1 hour
Authors
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May support slow IV amiodarone in severe LV dysfunction; hypothesis-generating and leaves open need for RCTs.
Does slow intravenous amiodarone restore sinus rhythm and improve hemodynamics in critically ill patients with acute atrial fibrillation or flutter and severely depressed left ventricular function (LVEF < 15%)?
Slow intravenous amiodarone (300 mg over 1 hour) is an effective and hemodynamically well-tolerated therapy for acute atrial fibrillation/flutter in critically ill patients with severely depressed LV systolic function.
Anand Kumar (1996) studied this question.
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