Key result
Detectable peripheral neuropathy reduced the sensitivity of the ankle-brachial pressure index from 71% to 38% and the specificity of the toe-brachial pressure index from 81% to 61%.
Why the study?
Do foot pulses, ABPI, TBI, and Doppler waveform analysis accurately detect lower-limb PAOD in individuals with and without diabetes and peripheral neuropathy?
Population
68 individuals with no critical ischemia, grouped by the presence or absence of diabetes, clinically…
Comparison
Screening methods for lower-limb PAOD including… vs Color duplex imaging
Design
Cross-sectional
Authors
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Neuropathy may compromise ABPI and TBI accuracy for PAOD screening in diabetes; leaves open prospective validation of waveform analysis.
Observational (n=68)
Do foot pulses, ABPI, TBI, and Doppler waveform analysis accurately detect lower-limb PAOD in individuals with and without diabetes and peripheral neuropathy?
Qualitative waveform analysis and TBI are more effective than ABPI and foot pulses for screening lower-limb PAOD in diabetic patients, particularly those with peripheral neuropathy.
Williams et al. (2005) conducted an observational in Lower-limb peripheral arterial occlusive disease (PAOD) in diabetes (n=68). Diabetes with detectable peripheral neuropathy vs. Absence of diabetes or peripheral neuropathy was evaluated on Diagnostic accuracy (sensitivity and specificity) of screening methods for PAOD. Detectable peripheral neuropathy reduced the sensitivity of the ankle-brachial pressure index from 71% to 38% and the specificity of the toe-brachial pressure index from 81% to 61%.
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