Key result
Ca2+ flux through L-type Ca2+ channels alone is not sufficient to fully activate contraction in trout atrial myocytes at room temperature, accounting for only 30-40% of required Ca2+ binding.
In contrast to previous reports from other lower vertebrates, Ca2+ flux through L-type Ca2+ channels alone is not sufficient to fully activate contraction in trout atrial myocytes at room temperature.
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Challenges prior lower vertebrate data; hypothesis-generating for species-specific Ca2+ handling in fish myocytes.
Hove‐Madsen et al. (1998) studied this question. Isoproterenol, cAMP, and varying EGTA concentrations vs. Basal conditions was evaluated on Contribution of L-type Ca2+ current to the activation of contraction. Ca2+ flux through L-type Ca2+ channels alone is not sufficient to fully activate contraction in trout atrial myocytes at room temperature, accounting for only 30-40% of required Ca2+ binding.
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