Key result
SCAI shock stage E linked to ~185-fold higher in-hospital mortality vs stage A.
Why the study?
The predictive behavior of the SCAI cardiogenic shock classification in patients with primary acute heart failure is not fully known.
Does the SCAI Cardiogenic Shock Classification predict in-hospital and long-term mortality in patients with primary acute heart failure?
Cohort (n=856)
No
Does the SCAI Cardiogenic Shock Classification predict in-hospital and long-term mortality in patients with primary acute heart failure?
Hazard Ratio: 185
Absolute Event Rate: 90.6% vs 0.6%
p-value: p=<0.001
The SCAI cardiogenic shock classification provides robust risk stratification for in-hospital and long-term mortality in patients presenting specifically with primary acute heart failure.
May support SCAI staging for risk stratification in acute HF; extends validation to this population but should not yet change practice.
Background: SCAI classification in cardiogenic shock is simple and suitable for rapid assessment. Its predictive behavior in patients with primary acute heart failure (AHF) is not fully known. We aimed to evaluate the ability of the SCAI classification to predict in-hospital and long-term mortality in AHF. Methods: We conducted a single-center study and performed a retrospective analysis of prospectively collected data of consecutive patients admitted with AHF between 2015 and 2020. The primary end points were in-hospital and long-term mortality from all causes. Results: = .1). Conclusions: In a cohort of patients with AHF, SCAI cardiogenic shock classification was associated with in-hospital and long-term mortality. This finding supports the rationale of the classification in this setting.
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Burgos et al. (2022) conducted a cohort in Acute Heart Failure (AHF) (n=856). SCAI Cardiogenic Shock Classification vs. Stage A (at risk) was evaluated on In-hospital mortality (HR 185, p=<0.001). Higher SCAI cardiogenic shock stages were significantly associated with increased in-hospital mortality, with an adjusted hazard ratio of 185 for Stage E compared to Stage A.
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