Key result
During the transition to loaded pedaling, the kinetics of alveolar and leg O2 uptake were similar (half times 25.5 vs 27.9 s), indicating bulk O2 delivery does not limit muscle O2 uptake kinetics.
Population
6 trained human subjects, mean age 22.8 +/- 4.4 years, maximal O2 uptake 59.1 +/- 5.3 ml.kg-1.min-1
Comparison
Transition from unloaded pedaling to loaded… vs Unloaded pedaling (baseline)
Design
Other
Authors
Loading...
Questions bulk O2 delivery as limiter of muscle VO2 kinetics; extends models but remains hypothesis-generating in small samples.
During the on-transition of exercise, the kinetics of alveolar VO2 and leg muscle VO2 are similar, indicating that bulk delivery of O2 to working muscles does not limit muscle VO2 kinetics.
Grassi et al. (1996) studied Healthy trained subjects (n=6). Transition from unloaded to loaded pedaling vs. Unloaded pedaling was evaluated on Half times of the responses among variables (VO2A, Qleg, leg O2 delivery, (Ca - Cv)O2leg, and VO2leg). During the transition to loaded pedaling, the kinetics of alveolar and leg O2 uptake were similar (half times 25.5 vs 27.9 s), indicating bulk O2 delivery does not limit muscle O2 uptake kinetics.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: