Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 1, 1993The Thoracic and Cardiovascular Surgeon

Oral Sotalol Reduces the Incidence of Atrial Fibrillation after Coronary Artery Bypass Surgery

View Full Paper
Ask AI
Bookmark
Share

Key result

Oral sotalol reduces the incidence of atrial fibrillation after coronary artery bypass surgery.

Why the study?

Does oral sotalol reduce the incidence of atrial fibrillation in patients undergoing coronary artery bypass surgery?

Population

101 patients undergoing coronary artery bypass surgery.

Comparison

Oral pre- and postoperative treatment with… vs Half the preoperative beta-blocking dose…

Design

RCT, randomized

Follow-up

postoperative course

Authors

UNUlla NyströmAllergan (Ireland)NENils EdvardssonElectrophysiologyHBHåkan BerggrenDrottning Silvias barn- och ungdomssjukhus

Discussion

Loading...

Member takes

Implication

Supports sotalol prophylaxis post-CABG with monitoring; confirms benefit over standard beta-blockers in RCT.

Structured PICO

Does oral sotalol reduce the incidence of atrial fibrillation in patients undergoing coronary artery bypass surgery?

P
Population
101 patients undergoing coronary artery bypass surgery.
I
Intervention
Oral pre- and postoperative treatment with sotalol.
C
Comparator
Half the preoperative beta-blocking dose according to the routine of the department.
O
Outcome
Incidence of atrial fibrillation.hard clinical

Oral sotalol significantly reduces the incidence of postoperative atrial fibrillation after coronary artery bypass surgery compared to routine beta-blocker dosing, though it requires careful dose titration due to side effects.

Cite This Study

Nyström et al. (1993) studied Atrial Fibrillation after Coronary Artery Bypass Surgery. Oral Sotalol was evaluated on Incidence of Atrial Fibrillation. Oral sotalol reduces the incidence of atrial fibrillation after coronary artery bypass surgery.

synapsesocial.com/papers/6a23791c003b3cd7fea5d8bfhttps://doi.org/10.1055/s-2007-1013817

Topics

Atrial fibrillationPersistent AF managementAnticoagulation in AFAF ablation outcomes
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Sotalol and Metoprolol in the Prevention of Atrial Fibrillation After Coronary Artery Bypass Surgery1998 · 98 citations
  2. 2Significance of Supraventricular Tachyarrhythmias After Coronary Artery Bypass Graft Surgery and Their Prevention by Low-Dose Sotalol: A Prospective Double-Blind Randomized Placebo-Controlled Study1998 · 32 citations
  3. 3Does prophylactic sotalol and magnesium decrease the incidence of atrial fibrillation following coronary artery bypass surgery: a propensity-matched analysis2006 · 19 citations
  4. 4Intravenous sotalol for the treatment of atrial fibrillation and flutter after cardiopulmonary bypass. Comparison with disopyramide and digoxin in a randomised trial.1985 · 105 citations
  5. 5Metoprolol versus low-dose sotalol for prevention of high-risk post coronary artery bypass grafting atrial fibrillation2021