Key result
Following closure of secundum atrial septal defect, anterior mitral valve prolapse decreased from 28 to 17 of 53 patients, and the left ventricle became more circular (p<0.01).
Why the study?
Does closure of secundum atrial septal defect reduce the incidence of mitral valve prolapse and improve left ventricular geometry?
Population
77 patients with secundum atrial septal defect (ASD)
Comparison
Closure of ASD vs Pre-operative state
Design
Cross-sectional
Authors
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ASD closure may improve mitral valve and LV geometry; hypothesis-generating and requires prospective confirmation before practice change.
Cross-Sectional (n=77)
Does closure of secundum atrial septal defect reduce the incidence of mitral valve prolapse and improve left ventricular geometry?
p-value: p=<0.01
Surgical closure of secundum ASD reduces the incidence of anterior mitral valve prolapse and improves left ventricular geometry.
Kambe et al. (1981) conducted a cross-sectional in Secundum atrial septal defect (n=77). Closure of atrial septal defect vs. Pre-operative state was evaluated on Incidence of anterior mitral valve prolapse and left ventricular distortion ratio (p=<0.01). Following closure of secundum atrial septal defect, anterior mitral valve prolapse decreased from 28 to 17 of 53 patients, and the left ventricle became more circular (p<0.01).
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