Key result
Longterm anticoagulation with warfarin in home dialysis patients was associated with a high rate of hemorrhagic complications (41.7% of patients) compared to intermittent heparin.
Why the study?
Does longterm anticoagulation with warfarin increase the risk of hemorrhagic complications compared to intermittent heparin in home dialysis patients?
Population
125 home dialysis patients
Comparison
Longterm anticoagulation with warfarin to… vs Intermittent anticoagulation with heparin for…
Design
Cohort
Follow-up
Up to 7 years (average 2 years for warfarin patients)
Authors
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Supports caution against long-term warfarin in home dialysis; leaves open randomized trials of safer access strategies.
Cohort (n=125)
Does longterm anticoagulation with warfarin increase the risk of hemorrhagic complications compared to intermittent heparin in home dialysis patients?
Longterm warfarin therapy for maintaining arteriovenous shunts in hemodialysis patients carries an unacceptably high risk of severe hemorrhagic complications.
Biggers et al. (2008) conducted a cohort in Hemodialysis (n=125). Warfarin vs. Heparin was evaluated on Bleeding or hemorrhagic complications. Longterm anticoagulation with warfarin in home dialysis patients was associated with a high rate of hemorrhagic complications (41.7% of patients) compared to intermittent heparin.
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