Key result
Cardiotrophin-1 appears to play an important role in infarct scar formation and angiogenesis in the rat model of chronic myocardial infarction.
Cardiotrophin-1 is an IL-6 superfamily cytokine that plays a significant role in cardiac wound healing, infarct scar formation, and angiogenesis post-myocardial infarction.
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Hypothesis-generating for CT-1 modulation in post-MI repair; leaves open translation to human therapeutics.
Freed et al. (2005) conducted a review in Ischemic heart disease / myocardial infarction. Cardiotrophin-1 (CT-1) was evaluated. Cardiotrophin-1 appears to play an important role in infarct scar formation and angiogenesis in the rat model of chronic myocardial infarction.
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