Key result
Various animal models of cardiac fibrosis are reviewed to elucidate the functional consequences of collagen accumulation and factors regulating the cellular and molecular biology of fibrogenesis.
This review discusses various animal models used to study the functional consequences and molecular biology of cardiac fibrosis.
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Animal models elucidate fibrosis effects on stiffness and function; leaves open translation of regulators to human therapies.
Sun et al. (2005) conducted a review in Cardiac fibrosis. Animal models of cardiac fibrosis was evaluated. Various animal models of cardiac fibrosis are reviewed to elucidate the functional consequences of collagen accumulation and factors regulating the cellular and molecular biology of fibrogenesis.