Key result
The proSCANNED score, a simplified 8-variable bedside prognostic tool, demonstrated moderate discrimination for predicting 1-year mortality in heart failure patients with an AUC of 0.71.
Why the study?
Existing Heart Failure risk scores are accurate but have limited clinical applicability, creating a need for a simple predictive tool to improve patient follow-up.
Does the proSCANNED score accurately predict 1-year mortality in outpatients with stable heart failure?
Cohort (n=447)
Open-label
Yes
Does the proSCANNED score accurately predict 1-year mortality in outpatients with stable heart failure?
The proSCANNED score is a simple, 8-item bedside tool that provides moderate discrimination for predicting 1-year mortality in stable heart failure patients.
May aid bedside risk stratification in stable HF outpatients; hypothesis-generating and requires prospective validation before clinical adoption.
A simple and accurate prognostic tool for Heart Failure (HF) patients is critical to improve follow-up. Different risk scores are accurate but with limited clinical applicability. The current study aims to derive and validate a simple predictive tool for HF prognosis. French outpatients with stable HF of two university hospitals were included in the derivation (N = 134) or in the validation (N = 274) sample and followed up for a median of 23 months. Potential predictors were variables with known association with mortality and easily available. The proSCANNED risk score was derived using a parametric survival model on complete case data; it includes 8 binary variables and its values are 0-8. In the validation sample, the ability of the score to discriminate the 1-year vital status was moderate (AUC = 0.71, IC95% = [0.64-0.71]). However, the stratification of the score in three groups showed a good calibration for patients in the low- and medium-risk risk group. The proSCANNED score is an easy-to-use tool in clinical practice with a good discrimination, stability, and calibration sufficient to improve the medical care of patients. Other follow up studies are necessary to assess score applicability in larger populations, and its impact.
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Duflos et al. (2021) conducted a cohort in Heart Failure (n=447). proSCANNED score was evaluated on 1-year mortality (AUC 0.71, 95% CI 0.64-0.79). The proSCANNED score, a simplified 8-variable bedside prognostic tool, demonstrated moderate discrimination for predicting 1-year mortality in heart failure patients with an AUC of 0.71.
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