Key result
Atrial fibrillation in patients with obstructive sleep apnea was significantly associated with higher mean platelet volume (9.8 vs 8.4 fL; P<0.001) and apnea hypopnea index.
Why the study?
Is atrial fibrillation associated with increased mean platelet volume and apnea hypopnea index in patients with obstructive sleep apnea?
Population
90 patients (aged 50-80 years) with obstructive sleep apnea syndrome (OSAS)
Design
Cross-sectional
Authors
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AF associated with higher MPV in OSA; hypothesis-generating, prospective studies needed before clinical use.
Observational (n=90)
Is atrial fibrillation associated with increased mean platelet volume and apnea hypopnea index in patients with obstructive sleep apnea?
Odds Ratio: 2.41 (95% CI 1.36–5.26)
Absolute Event Rate: 9.8% vs 8.4%
p-value: p=< .004
In patients with obstructive sleep apnea, the presence of atrial fibrillation is associated with significantly higher mean platelet volume and apnea hypopnea index.
Akyüz et al. (2014) conducted an observational in Obstructive sleep apnea syndrome (OSAS) (n=90). Atrial fibrillation vs. Normal sinus rhythm was evaluated on Mean platelet volume (OR 2.41, 95% CI 1.36-5.26, p=< .004). Atrial fibrillation in patients with obstructive sleep apnea was significantly associated with higher mean platelet volume (9.8 vs 8.4 fL; P<0.001) and apnea hypopnea index.
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