Why the study?
Elevated platelet activation is closely linked to cardiovascular complications, but the influence of OSAS on platelet activation is not fully understood.
Does Obstructive Sleep Apnea Syndrome severity affect mean platelet volume?
Comparison
Control group vs mild, moderate, and severe OSAS groups based on AHI
Design
Retrospective observational study
Key result
Obstructive Sleep Apnea syndrome severity was not significantly associated with differences in mean platelet volume compared to controls among 192 patients.
Authors
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MPV unrelated to OSAS severity in this cohort; leaves open platelet activation as a cardiovascular risk mediator.
Observational (n=192)
Does Obstructive Sleep Apnea Syndrome severity affect mean platelet volume?
Obstructive Sleep Apnea Syndrome severity does not appear to significantly influence mean platelet volume, a marker of platelet activation.
Geçkil et al. (2020) conducted an observational in Obstructive Sleep Apnea syndrome (n=192). Obstructive Sleep Apnea syndrome (OSAS) vs. Control group (AHI < 5) was evaluated on Mean platelet volume (MPV). Obstructive Sleep Apnea syndrome severity was not significantly associated with differences in mean platelet volume compared to controls among 192 patients.