Key result
Hysterectomy with or without bilateral oophorectomy was associated with lower carotid artery compliance compared to no hysterectomy (0.66 and 0.71 vs 0.89 mm/mm Hg × 10; P<0.05).
Why the study?
Does hysterectomy with or without bilateral oophorectomy increase arterial stiffening in healthy estrogen-deficient postmenopausal women?
Population
103 healthy estrogen-deficient postmenopausal women
Comparison
Hysterectomy with or without bilateral… vs No hysterectomy and no bilateral oophorectomy
Design
Cross-sectional
Authors
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Should not yet change hysterectomy decisions or prompt screening; leaves open causal role in postmenopausal arterial stiffening.
Cross-Sectional (n=103)
Does hysterectomy with or without bilateral oophorectomy increase arterial stiffening in healthy estrogen-deficient postmenopausal women?
Absolute Event Rate: 0.66% vs 0.89%
p-value: p=<0.05
Hysterectomy, with or without bilateral oophorectomy, is associated with greater large artery stiffening in estrogen-deficient postmenopausal women, independent of traditional cardiovascular risk factors.
Gavin et al. (2012) conducted a cross-sectional in Estrogen-deficient postmenopausal women (n=103). Hysterectomy with or without bilateral oophorectomy vs. No hysterectomy was evaluated on Carotid artery compliance (p=<0.05). Hysterectomy with or without bilateral oophorectomy was associated with lower carotid artery compliance compared to no hysterectomy (0.66 and 0.71 vs 0.89 mm/mm Hg × 10; P<0.05).
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