Key result
American Indian and Alaska Native male veterans undergoing major noncardiac surgery had a higher risk of 30-day all-cause mortality compared with Caucasian men (adjusted OR 1.56; 95% CI 1.04-2.35).
Why the study?
Does American Indian and Alaska Native race increase the risk of 30-day surgical morbidity or mortality compared to Caucasian race in male veterans undergoing major noncardiac surgery?
Cohort (n=4,419)
Yes
Does American Indian and Alaska Native race increase the risk of 30-day surgical morbidity or mortality compared to Caucasian race in male veterans undergoing major noncardiac surgery?
Odds Ratio: 1.56 (95% CI 1.04–2.35)
American Indian and Alaska Native male veterans face a significantly higher risk of 30-day postoperative mortality after major noncardiac surgery compared to Caucasian veterans.
May warrant closer perioperative monitoring in AI/AN veterans; leaves open whether disparities persist in modern cohorts or other populations.
BACKGROUND: Few studies have examined surgical risk factors and outcomes in American Indians and Alaska Natives (AI/ANs). My colleagues and I sought to determine if prevalence of preoperative risk factors for morbidity and mortality differed between male AI/AN and Caucasian surgical patients, and to determine if AI/ANs had an increased risk of surgical morbidity or mortality. STUDY DESIGN: We obtained data from the Veterans Affairs National Surgical Quality Improvement Program on major, noncardiac, surgical procedures performed between 1991 and 2002 for all AI/AN men (n = 2,155) and a random sample of Caucasian men (n = 2,264), matched by facility. Chi-square and t-test analyses were used to assess differences in preoperative risk factors between the two groups. Logistic regression was used to determine whether AI/AN race was independently associated with 30-day morbidity (defined as 1 or more of 21 postoperative complications) or 30-day all cause mortality after adjustment for major risk factors. RESULTS: Prevalence of major preoperative risk factors for morbidity and mortality often differed between the groups. Compared with Caucasians, AI/AN race did not predict morbidity (adjusted odds ratio, 0.92; 95% CI, 0.75-1.13), but AI/ANs were at higher risk for 30-day all cause postoperative mortality (adjusted odds ratio, 1.56; 95% CI, 1.04-2.35). CONCLUSIONS: Our results add postoperative mortality to health disparities experienced by AI/ANs. Future research should be conducted to identify other factors that contribute to this disparity.
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Alvord et al. (2005) conducted a cohort in Major, noncardiac, surgical procedures (n=4,419). American Indian and Alaska Native race vs. Caucasian race was evaluated on 30-day all cause postoperative mortality (OR 1.56, 95% CI 1.04-2.35). American Indian and Alaska Native male veterans undergoing major noncardiac surgery had a higher risk of 30-day all-cause mortality compared with Caucasian men (adjusted OR 1.56; 95% CI 1.04-2.35).
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