Key result
Ascending aortic aneurysm repair is linked to ~33% lower circumferential strain versus AVR or CABG.
Why the study?
Evaluating local biaxial deformation in the ascending aorta is critical for assessing tissue state and remodeling, but the absence of anatomical markers creates challenges in capturing this deformation.
Does intra-operative biaxial strain differ between patients undergoing aortic repair for aneurysms and those undergoing AVR/CABG?
Population
20 patients undergoing AVR and CABG surgery and 47 Aortic Repair surgery patients
Comparison
Aortic Repair surgery patients vs AVR and CABG surgery recipients
Authors
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Lower strain suggests greater aortic stiffness in aneurysm repair; hypothesis-generating for strain-based risk stratification pending prospective studies.
Cross-Sectional (n=67)
No
Does intra-operative biaxial strain differ between patients undergoing aortic repair for aneurysms and those undergoing AVR/CABG?
Absolute Event Rate: 0.02% vs 0.03%
p-value: p=0.028
Intra-operative biaxial strain measurements reveal that ascending aortas in patients undergoing aortic repair have significantly lower regional strains compared to those undergoing AVR/CABG, indicating increased stiffness.
Parikh et al. (2024) conducted a cross-sectional in Ascending thoracic aortic aneurysm and other cardiac conditions requiring open-chest surgery (n=67). Aortic Repair surgery (aneurysmatic aortas) vs. Aortic valve replacement or coronary artery bypass graft surgery (AVR/CABG) was evaluated on Mean circumferential strain (p=0.028). Patients undergoing Aortic Repair surgery for ascending aortic aneurysms exhibited significantly lower mean circumferential strain (median 0.02 vs 0.03, p=0.028) compared to patients undergoing AVR or CABG.
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