Key result
Circumferential pulmonary vein isolation significantly decreased continuous complex fractionated atrial electrograms from 18% to 12% of left atrial sites (P=0.02).
Why the study?
Does circumferential pulmonary vein isolation alter left atrial substrate characteristics in patients with atrial fibrillation?
Observational (n=72)
Does circumferential pulmonary vein isolation alter left atrial substrate characteristics in patients with atrial fibrillation?
Absolute Event Rate: 12% vs 18%
p-value: p=0.02
Complete PVI alters the distribution of complex fractionated atrial electrograms, and their persistent presence near high-frequency sites is important for AF maintenance.
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PVI may reduce continuous CFEs in AF; leaves open whether targeting persistent sites near high-frequency areas improves outcomes.
Lin et al. (2009) conducted an observational in Atrial fibrillation (n=72). Circumferential pulmonary vein isolation (PVI) vs. Pre-PVI baseline was evaluated on Continuous complex fractionated atrial electrograms (CFEs) as a percentage of left atrial sites (p=0.02). Circumferential pulmonary vein isolation significantly decreased continuous complex fractionated atrial electrograms from 18% to 12% of left atrial sites (P=0.02).
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