Key result
The presence of left atrial low voltage areas was associated with significantly lower 12-month arrhythmia-free survival in both paroxysmal (38% vs 76%, P=0.002) and persistent AF (27% vs 61%, P=0.015).
Why the study?
AF ablation with PVI has significantly lower success rates for persistent AF compared to paroxysmal AF, prompting evaluation of the impact of left atrial low voltage areas on ablation response.
Does the presence of left atrial low voltage areas predict arrhythmia recurrence in patients undergoing first-time radiofrequency ablation for atrial fibrillation?
Population
160 consecutive patients undergoing first-time radiofrequency AF ablation (53% PAF)
Comparison
Presence of left atrial low voltage areas vs absence of low voltage areas
Design
Cohort study
Follow-up
12 months
Authors
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LA LVA mapping may identify persistent AF patients with lower ablation success; leaves open whether voltage-guided ablation improves outcomes.
Cohort (n=160)
Does the presence of left atrial low voltage areas predict arrhythmia recurrence in patients undergoing first-time radiofrequency ablation for atrial fibrillation?
The presence of left atrial low voltage areas is an independent predictor of arrhythmia recurrence after first-time pulmonary vein isolation, and its absence identifies persistent AF patients who respond well to PVI alone.
Ahmed‐Jushuf et al. (2019) conducted a cohort in Atrial fibrillation (n=160). Left atrial low voltage areas (LVA) vs. Absence of left atrial low voltage areas was evaluated on Recurrence of any sustained atrial arrhythmia during 12 months follow-up. The presence of left atrial low voltage areas was associated with significantly lower 12-month arrhythmia-free survival in both paroxysmal (38% vs 76%, P=0.002) and persistent AF (27% vs 61%, P=0.015).
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