Why the study?
Left atrial low-voltage areas may promote atrial fibrillation, but the efficacy of low-voltage-area ablation for preventing arrhythmia recurrence had not been determined.
Does low-voltage area ablation in addition to pulmonary vein isolation reduce AF or AT recurrence in patients with persistent AF and left atrial LVAs?
Comparison
PVI plus LVA ablation vs PVI alone
Design
Multicenter randomized controlled trial
Follow-up
1 year
Authors
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Adjunctive LVA ablation is not superior to PVI alone; leaves open possible benefit in extensive remodeling subgroups.
Does low-voltage area ablation in addition to pulmonary vein isolation reduce AF or AT recurrence in patients with persistent AF and left atrial LVAs?
The addition of low-voltage area ablation to pulmonary vein isolation does not significantly improve 1-year freedom from atrial arrhythmias in patients with persistent atrial fibrillation.
Masuda et al. (2025) studied this question.
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