Key result
Low-voltage areas ≤24% in nonparoxysmal AF are linked to ~25% higher absolute AF freedom post-PVI.
Why the study?
Does the extent of low-voltage areas and high-dominant frequencies predict atrial fibrillation recurrence after pulmonary vein isolation in patients with nonparoxysmal atrial fibrillation?
Population
70 patients with nonparoxysmal atrial fibrillation (including 41 with persistent AF)
Comparison
Circumferential pulmonary vein isolation… vs Patients with low-voltage areas ≤24% vs >24% of…
Design
Cohort
Follow-up
12 months
Authors
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LVA extent may aid recurrence risk stratification before PVI; leaves open whether ablation should be tailored to LVA burden.
Observational (n=70)
Does the extent of low-voltage areas and high-dominant frequencies predict atrial fibrillation recurrence after pulmonary vein isolation in patients with nonparoxysmal atrial fibrillation?
Absolute Event Rate: 78.6% vs 53.8%
p-value: p=0.020
In patients with nonparoxysmal atrial fibrillation, low-voltage areas exceeding 24% of the left atrium are associated with higher rates of AF recurrence after pulmonary vein isolation.
Kumagai et al. (2018) conducted an observational in nonparoxysmal atrial fibrillation (n=70). Pulmonary vein isolation vs. Low-voltage areas >24% was evaluated on AF freedom without antiarrhythmic drugs (p=0.020). Patients with nonparoxysmal AF and low-voltage areas ≤24% had significantly higher 12-month AF freedom after pulmonary vein isolation compared to those with >24% (78.6% vs 53.8%, P=0.020).
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