What does this research mean for the field?

Multicomponent antioxidant supplementation significantly improves semen quality and pregnancy outcomes in men with mild to moderate semen abnormalities, but provides no benefit for those with severe oligoasthenoteratozoospermia. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aimed to assess the effects of a multi-component antioxidant supplement on semen parameters and pregnancy rates in infertile men.

June 6, 2026The Journal of Sexual Medicine

(616) Effect of Multicomponent Antioxidant Therapy on Semen Parameters and Pregnancy Outcomes in Infertile Men

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Authors

MBM BoikoBogomolets National Medical University OBO BoikoHospital de Cruces OCO ChernichenkoCentral Clinical Hospital

Discussion

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Overview

Randomized trial evaluates improved semen parameters and pregnancy rates in infertile men using antioxidant therapy, indicating potential benefits for subfertility.

Key Points

This study aimed to assess the effects of a multi-component antioxidant supplement on semen parameters and pregnancy rates in infertile men.
Prospective analytical study conducted from September 2021 to October 2024.
Male patients diagnosed with infertility received an oral antioxidant supplement twice daily for 3-9 months.
Baseline and follow-up semen analyses were performed to assess various parameters.
83.7% of participants had at least one abnormal semen parameter at baseline.
41.6% of participants achieved pregnancy after treatment, with the highest rate in those with normal parameters (80%).
Significant improvements in sperm concentration, motility, and morphology were observed in most groups after treatment.

Cite This Study

Boiko et al. (2026) studied this question.

synapsesocial.com/papers/6a23b9ca71a5da9775e75a18 https://doi.org/10.1093/jsxmed/qdag118.544

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June 6, 2026The Journal of Sexual Medicine

(616) Effect of Multicomponent Antioxidant Therapy on Semen Parameters and Pregnancy Outcomes in Infertile Men

View Full Paper

Ask AI

Bookmark

Authors

MBM BoikoBogomolets National Medical University OBO BoikoHospital de Cruces OCO ChernichenkoCentral Clinical Hospital

Discussion

Member takes

Overview

Randomized trial evaluates improved semen parameters and pregnancy rates in infertile men using antioxidant therapy, indicating potential benefits for subfertility.

Key Points

This study aimed to assess the effects of a multi-component antioxidant supplement on semen parameters and pregnancy rates in infertile men.
Prospective analytical study conducted from September 2021 to October 2024.
Male patients diagnosed with infertility received an oral antioxidant supplement twice daily for 3-9 months.
Baseline and follow-up semen analyses were performed to assess various parameters.
83.7% of participants had at least one abnormal semen parameter at baseline.
41.6% of participants achieved pregnancy after treatment, with the highest rate in those with normal parameters (80%).
Significant improvements in sperm concentration, motility, and morphology were observed in most groups after treatment.

Cite This Study

Boiko et al. (2026) studied this question.

synapsesocial.com/papers/6a23b9ca71a5da9775e75a18 https://doi.org/10.1093/jsxmed/qdag118.544

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