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June 6, 2026The Journal of Sexual Medicine

(611) Comparative Analysis of the Complex/Combined Treatment for 60 Men With Erectile Dysfunction Due to Metabolic Syndrome and Venogenic Dysfunction: An Evidence - Based Study

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Authors

ZMZ MarshaniaNNN Nodia

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Overview

Evidence-based study compares treatment outcomes for metabolic syndrome and venogenic erectile dysfunction.

Key Points

  • This study aims to compare treatment outcomes for erectile dysfunction caused by metabolic syndrome and venogenic dysfunction.
  • Included 60 male patients diagnosed with erectile dysfunction, divided into two groups (30 with metabolic syndrome, 30 with venogenic dysfunction).
  • Evaluated testosterone levels, lipid profiles, and erectile function using the IIEF-5 questionnaire.
  • Applied different treatment regimens: aphrodisiacs and PDE-5 inhibitors for metabolic syndrome; venotonics and PDE-5 inhibitors for venogenic dysfunction.
  • 87% of patients with metabolic syndrome reported improvement after treatment, compared to 97% in the venogenic dysfunction group.
  • Testosterone levels significantly increased for both groups after treatment, with P = 0.022 for metabolic syndrome and P = 0.001 for venogenic dysfunction.
  • A strong correlation (P < 0.001) between pre- and post-treatment testosterone levels was observed, indicating a more pronounced response in the venogenic dysfunction group.

Cite This Study

Marshania et al. (2026) studied this question.

synapsesocial.com/papers/6a23bb7971a5da9775e76e62https://doi.org/10.1093/jsxmed/qdag118.539
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Also Consider

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  1. 1(800) Beyond the IIEF Score: Biochemical and Hormonal Signatures Across Erectile Dysfunction Severity2026
  2. 2(749) Association Between Metabolic Syndrome Severity and Incident Erectile Dysfunction: A Retrospective Cohort Analysis Using a National Health Database2026
  3. 3REVITALISE: A Large Observational Study Assessing the Safety and Effectiveness of Vardenafil in Men With Erectile Dysfunction and Metabolic Syndrome2016 · 7 citations
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  5. 5Advances in Erectile Dysfunction Management: What Does Work2026