Key result
SOFA-2 updates the original SOFA score to reflect modern diagnostics and organ dysfunction therapies.
Why the study?
The SOFA score, proposed 30 years ago, requires corrections due to changes in diagnostic methods and therapy of organ dysfunction.
The SOFA-2 score updates the 30-year-old original SOFA score to account for modern diagnostic methods and therapies for organ dysfunction.
SOFA-2 may refine organ dysfunction assessment in current practice; leaves open prospective validation of improved ICU prognostication versus original SOFA.
The SOFA score was proposed 30 years ago. This scale is now requiring corrections due to changes in diagnostic methods and therapy of organ dysfunction. This review presents the background of the SOFA-2 score, summarizes the main stages and principles of development. The algorithm for the SOFA-2 score and its differences from original SOFA score are also discussed. The authors analyze advantages and limitations of the updated score.
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Smetkin et al. (2026) conducted a review in Organ dysfunction. SOFA-2 score vs. Original SOFA score was evaluated. The SOFA-2 score updates the original SOFA score to account for changes in diagnostic methods and therapy of organ dysfunction.
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