What question did this study set out to answer?

To assess the prognostic value of postoperative inflammatory markers and their changes in predicting outcomes after emergency cerclage in women with prolapsed membranes.

June 6, 2026Journal of obstetrics and gynaecology research

Dynamic Systemic Inflammatory Markers for Predicting Perinatal Outcomes After Emergency Cerclage in Women With Membrane Prolapse

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BTBüşra TsakirAntalya Eğitim ve Araştırma Hastanesi GBGül Alkan BülbülAntalya Eğitim ve Araştırma Hastanesi EAElif Ayan AvcıAntalya Eğitim ve Araştırma Hastanesi

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Implication

Retrospective cohort study evaluates postoperative inflammatory markers for cerclage outcomes, indicating potential for improved pregnancy management.

Key Points

To assess the prognostic value of postoperative inflammatory markers and their changes in predicting outcomes after emergency cerclage in women with prolapsed membranes.
Single-center retrospective cohort study including 34 singleton pregnancies with prolapsed membranes treated with emergency McDonald cerclage.
Measured neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI) preoperatively and 48-72 hours postoperatively.
Calculated Δ values for the inflammatory markers.
Postoperative inflammatory markers were significantly higher in the cerclage failure group.
Postoperative NLR had an AUC of 0.825 with a cutoff ≥ 5.78, showing sensitivity of 80.0% and specificity of 84.2%.
Postoperative NLR negatively correlated with pregnancy prolongation (ρ = -0.561, p < 0.001).

Cite This Study

Tsakir et al. (2026) studied this question.

synapsesocial.com/papers/6a23bb9a71a5da9775e77031 https://doi.org/10.1111/jog.70347

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Implication

Retrospective cohort study evaluates postoperative inflammatory markers for cerclage outcomes, indicating potential for improved pregnancy management.

Dynamic Systemic Inflammatory Markers for Predicting Perinatal Outcomes After Emergency Cerclage in Women With Membrane Prolapse

Discussion

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Implication

Key Points

Cite This Study

Dynamic Systemic Inflammatory Markers for Predicting Perinatal Outcomes After Emergency Cerclage in Women With Membrane Prolapse

Discussion

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Implication

Key Points

Cite This Study

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