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June 6, 2026Discover OncologyOpen Access

Prognostic impact of multiple N2 stations in patients with non small cell lung cancer

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Authors

GIGizem IşıkATAkif TurnaSYSibel Yurt

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Overview

Randomized trial finds similar survival rates in patients with single vs multiple N2 stations, indicating key prognostic factors.

Key Points

  • This study examines the prognostic impact of multiple N2 lymph node stations in non-small cell lung cancer (NSCLC) patients.
  • Included 149 patients with N2 involvement post-lung resection from 2002 to 2023 across 7 clinics.
  • Compared single-station (n=98) vs multiple-station (n=51) N2 involvement using statistical tests.
  • Conducted survival analysis with Kaplan-Meier method and Cox regression analysis.
  • No significant difference in overall survival between single-station (p=0.675) and multiple-station N2 involvement.
  • Adenocarcinoma diagnosis (p=0.024) and neoadjuvant therapy (p<0.001) significantly impact survival outcomes.
  • Pathological diagnosis and neoadjuvant therapy identified as independent negative prognostic factors (p=0.046 and p<0.001).

Cite This Study

Işık et al. (2026) studied this question.

synapsesocial.com/papers/6a23bc2a71a5da9775e779b2https://doi.org/10.1007/s12672-026-05325-1
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