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May 24, 2026Journal of Cardiothoracic SurgeryOpen Access

Prognostic factors in resected non-small cell lung cancer with pathological N1 lymph node involvement: a survival analysis

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Authors

EKEmrah KarciIzmir UniversityFMFatma MutluEskişehir City HospitalBABatuhan Erhan AktaşDokuz Eylül University

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Overview

Survival analysis evaluates prognostic factors in resected non-small cell lung cancer cases, suggesting key predictors affecting outcomes.

Key Points

  • This analysis focuses on identifying factors that influence survival in resected NSCLC patients with N1 lymph node metastasis.
  • Retrospective analysis of 66 NSCLC patients treated between 2010 and 2020
  • Survival times evaluated using the Kaplan–Meier method and Cox regression analysis
  • Assessment of clinical, demographic, and histopathological data
  • Mean overall survival was 59.7 months, with disease-free survival of 52.0 months
  • Histological subtype and occult lymph node metastasis were independent prognostic factors (p < 0.05)
  • Factors like tumor location and visceral pleural invasion correlated significantly with survival

Cite This Study

Karci et al. (2026) studied this question.

synapsesocial.com/papers/6a1296c748a0ea1665673d1ahttps://doi.org/10.1186/s13019-026-04041-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic Factors in Resected Non-Small Cell Lung Cancer with Pathological N1 Lymph Node Involvement: A Survival Analysis2025
  2. 2Prognostic significance of nodal subclassification and adjuvant therapy in surgically treated T1-4N1-2M0 non-small cell lung cancer: a single-center retrospective study2026
  3. 3Rethinking pN1 Disease in Non-Small Cell Lung Cancer: Anatomical Subclassification, Surgical Extent, and Survival Outcomes2026
  4. 4Hilar Lymphadenectomy Is Associated With Improved Disease‐Free Survival in Pathologically N0 Non‐Small Cell Lung Cancer2025
  5. 5Prognostic impact of multiple N2 stations in patients with non small cell lung cancer2026