Key result
Aerobic training reduces morning BP surge in postmenopausal women but blunts nocturnal dipping in multimorbidity.
Why the study?
Postmenopausal women face increased risks for cardiometabolic diseases due to hormonal changes, but evidence for the effectiveness of exercise therapy in those with multimorbidity remains limited.
Does a 12-week aerobic training program improve ambulatory blood pressure, blood pressure variability, and arterial stiffness in postmenopausal women with and without cardiometabolic multimorbidity?
Does a 12-week aerobic training program improve ambulatory blood pressure, blood pressure variability, and arterial stiffness in postmenopausal women with and without cardiometabolic multimorbidity?
A 12-week aerobic training program improves morning blood pressure surge in postmenopausal women, though it may reduce nocturnal dipping in those with multimorbidity.
Answers are grounded in this paper and cite their sources.
May blunt morning surge but reduce dipping in multimorbidity; leaves open net benefit of aerobic training in postmenopausal women.
BACKGROUND: Multimorbidity represents significant public health challenges, particularly in postmenopausal women, who experience increased risks for cardiovascular and metabolic diseases because of hormonal changes. While exercise therapy has shown promise in enhancing health outcomes for individuals with multimorbidity, evidence of its effectiveness in this specific population remains limited. OBJECTIVE: This study investigated the effects of a 12-week aerobic training program on ambulatory blood pressure, blood pressure variability, and arterial stiffness in postmenopausal women with and without cardiometabolic multimorbidity. METHODS: A controlled, quasi-experimental study was conducted with 41 women divided into two groups: SINGLE (one cardiometabolic condition; n = 18) and MULTI (multimorbidity; n = 23). Participants underwent aerobic training three times a week. Ambulatory blood pressure, blood pressure variability, and arterial stiffness were assessed before and after the intervention. RESULTS: A significant reduction in diastolic nocturnal dipping was observed only in the MULTI group (interaction P = 0.019), decreasing from 10 ± 12% to 7 ± 9%. Both groups showed a significant reduction in systolic (SINGLE: 21 to 8; MULTI: 19 to 7) and diastolic morning surge (SINGLE: 16 to 11; MULTI: 16 to 6) (time P < 0.001). No interaction effect was observed in arterial stiffness parameters. An exercise intervention effect (P = 0.001) indicated an increase in augmentation index (%) in both groups following aerobic training. CONCLUSION: A 12-week aerobic program improved morning surge blood pressure in postmenopausal women. However, the MULTI group showed reduced nocturnal dipping.
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Costa et al. (2026) studied Cardiometabolic multimorbidity (n=41). Aerobic training program vs. SINGLE group (one cardiometabolic condition) was evaluated on Diastolic nocturnal dipping (p=0.019). A 12-week aerobic training program reduced morning blood pressure surge in postmenopausal women (P<0.001), but reduced diastolic nocturnal dipping in those with multimorbidity (P=0.019).
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