What question did this study set out to answer?

Evaluate hematocrit and an anthropometric formula against radiolabeled albumin for plasma volume estimation.

Agreement Between Methods Assessing Changes in Plasma Volume During Fluid Therapy—A Post Hoc Analysis of a Randomized Trial

View Full Paper

Ask AI

Bookmark

Authors

Randomized trial evaluates plasma volume estimation methods in postoperative patients, revealing limitations of simpler approaches.

Evaluate hematocrit and an anthropometric formula against radiolabeled albumin for plasma volume estimation.
Post hoc analysis of randomized trial involving 64 postoperative patients.
Plasma volumes measured at baseline, 30 min, and 180 min using radiolabeled albumin as reference method.
Agreement between methods assessed using Bland–Altman plots.
Anthropometric method: mean difference from reference was −0.1 mL/kg (95% CI –2.1 to 1.8).
Calibrated method: mean difference from reference was −0.1 mL/kg (95% CI –0.9 to 0.7).
Both simpler methods lacked precision compared to the reference method for assessing plasma volume changes.

Grubb et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark