Why the study?
Does a theoretical mathematical model using hematocrit changes after a fluid bolus accurately predict actual blood volume?
Population
9 unique subjects derived from a commercially used FDA-approved semi-automated blood volume analyzer
Comparison
Theoretical mathematical model to estimate total… vs Actual blood volume measures from the…
Design
Other
Authors
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Hypothesis-generating for hematocrit-based volume estimation; prospective validation required before any clinical adoption.
Does a theoretical mathematical model using hematocrit changes after a fluid bolus accurately predict actual blood volume?
A novel mathematical model using hematocrit changes before and after a fluid bolus shows high correlation with actual blood volume, offering a potential method for titrating IV fluids.
D’Angelo et al. (2014) studied this question.
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