(246) Quality and Reliability of TikTok Videos on Peyronie’s Disease: A Cross-Sectional Study

Introduction Peyronie’s disease (PD) affects up to 9% of men and causes penile curvature and sexual dysfunction. Barriers such as stigma and limited specialist access lead many patients to seek information online. TikTok, with over one billion users, hosts a growing volume of sexual-health content, yet the accuracy of PD-related material has not been systematically evaluated. Objective To assess the reliability and educational quality of TikTok videos on PD and compare outcomes across creator type, content category, and accuracy classification. Methods The term “Peyronie’s disease” was searched on TikTok (September 2025) under the “Top” tab without user login. The first 50 English-language videos containing relevant medical or educational content were analysed. Duration, views, likes, comments, and source type (urologist, non-urologist, or patient) were recorded. Videos were categorized as educational or advertisements. Two urologists rated reliability based on the accuracy of urological information; discrepancies were resolved by consensus. Quality was evaluated using the validated modified 5-item DISCERN and Patient Education Materials Assessment Tool–Audio-visual (PEMAT-AV) instruments. Non-parametric comparisons were performed with Mann–Whitney U tests (p < 0.05). Results Fifty videos were analysed: 28 (56%) uploaded by urologists and 22 (44%) by non-urologists; no patient-generated videos were identified. Most were educational (72%), and 14 (28%) were advertisements. Only 19 videos (38%) were rated reliable, while 31 (62%) contained inaccurate or misleading information. Mean duration was 49, and median views were 27,000. Overall DISCERN and PEMAT-AV scores were 2.18 ± 1.21 and 12.22 ± 5.34, respectively. Urologist-generated videos achieved higher DISCERN scores than those created by non-urologists (2.46 vs. 1.82). Educational videos scored significantly higher on DISCERN than advertisements (2.50 vs 1.36, p = 0.008). Reliable videos were longer (p = 0.011) and had higher DISCERN (p = 0.001) and PEMAT-A (p = 0.004) scores, whereas engagement metrics did not differ by reliability (p > 0.05). Conclusions Most TikTok videos on Peyronie’s disease contained unreliable or incomplete medical information, though reliable videos demonstrated stronger educational structure and clarity. Short, visually focused clips often sacrificed accuracy. Given TikTok’s wide reach among younger audiences, improving the quality and reliability of men’s sexual-health information and encouraging active involvement of urological societies are essential to ensure accurate, evidence-based education on social media platforms. Disclosure No