Key result
Hepatic clearance of VLDL and TRL remnants is favored by lipolysis and the presence of apoBl, which is preferentially removed compared to apoBh.
Hepatic clearance of VLDL and TRL remnants is favored by lipolysis and the presence of the lower molecular weight fraction of apolipoprotein B (apoBl).
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Preclinical rat data implicate lipolysis and apoBl in TRL remnant clearance; leaves open human relevance.
Sparks et al. (1983) studied Lipid metabolism. 125I-labeled VLDL and TRL vs. Control perfusions with heat-treated postheparin plasma was evaluated on Hepatic clearance and degradation of apoBl vs apoBh. Hepatic clearance of VLDL and TRL remnants is favored by lipolysis and the presence of apoBl, which is preferentially removed compared to apoBh.
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