What question did this study set out to answer?

This research aims to understand the relationship between glucose tolerance and the development of hypertension in middle-aged men.

March 2, 1991BMJOpen Access

Glucose tolerance and blood pressure: long term follow up in middle aged men.

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Why the study?

Does glucose tolerance predict the development of hypertension in clinically healthy middle-aged men?

Population

1203 clinically healthy middle-aged men born during 1919-34 who did not receive an intervention in a primary…

Design

Cohort

Follow-up

up to 18 years

Authors

VSVeikko SalomaaPreventive Cardiology TSTimo StrandbergPreventive Cardiology HVHannu VanhanenAmerican Heart Association

Discussion

Member takes

Implication

May support glucose assessment for hypertension risk stratification in middle-aged men; leaves open causality and need for prospective validation.

Key Points

This research aims to understand the relationship between glucose tolerance and the development of hypertension in middle-aged men.
Retrospective analysis of health check-up data from middle-aged men in the late 1960s.
Follow-up examinations conducted in 1974, 1979, and 1986.
Subjects analyzed based on their blood glucose concentrations and blood pressure measurements.
Hypertensive men in 1986 had significantly higher blood glucose concentrations (p < 0.0001).
Men with higher glucose concentrations in 1968 showed increased blood pressure over time.
Men in the second and third tertiles of glucose concentration had a higher risk of hypertension (OR 1.71, 95% CI 1.05 to 2.77).

Structured PICO

Does glucose tolerance predict the development of hypertension in clinically healthy middle-aged men?

Population

1203 clinically healthy middle-aged men born during 1919-34 who did not receive an intervention in a primary prevention trial for cardiovascular disease.

Outcome

Development of hypertension (blood pressure measured in 1968, 1974, 1979, and 1986)surrogate

Blood glucose concentration one hour after a glucose load is an independent predictor of future hypertension in middle-aged men.

Cite This Study

Salomaa et al. (1991) studied this question.

synapsesocial.com/papers/6a23bdb99ed8aa0626a045a7 https://doi.org/10.1136/bmj.302.6775.493

Topics

Hypertension management

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Implication

May support glucose assessment for hypertension risk stratification in middle-aged men; leaves open causality and need for prospective validation.

Glucose tolerance and blood pressure: long term follow up in middle aged men.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Glucose tolerance and blood pressure: long term follow up in middle aged men.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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