Why the study?
The AFEQT questionnaire is typically measured only once in AF, but serial assessments may better reflect disease burden and prognostic risk over time.
Does serial assessment of AFEQT scores predict all-cause death and heart failure hospitalization in stable outpatients with atrial fibrillation?
Population
2,743 stable outpatients with AF referred to 11 hospitals in Japan
Comparison
Baseline, 12-month, and change in AFEQT overall summary scores
Design
Multicenter prospective registry study
Follow-up
Median 4.0 years
Key result
Higher current AFEQT overall summary scores were associated with a lower risk of death or heart failure hospitalization (HR 0.94; 95% CI 0.91-0.97 per 5-point increase).
Authors
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Serial AFEQT assessment may refine prognostication in stable AF outpatients; leaves open whether monitoring improves outcomes or warrants trials.
Cohort (n=2,743)
Yes
Does serial assessment of AFEQT scores predict all-cause death and heart failure hospitalization in stable outpatients with atrial fibrillation?
Hazard Ratio: 0.94 (95% CI 0.91–0.97)
Serial assessment of patient-reported health status using the AFEQT questionnaire provides better prognostic value for mortality and heart failure hospitalization in atrial fibrillation patients than a single baseline measurement.
Shiraishi et al. (2026) conducted a cohort in Atrial fibrillation (n=2,743). Current AFEQT overall summary score vs. Baseline AFEQT overall summary score was evaluated on all-cause death and heart failure (HF) hospitalization (HR 0.94, 95% CI 0.91-0.97). Higher current AFEQT overall summary scores were associated with a lower risk of death or heart failure hospitalization (HR 0.94; 95% CI 0.91-0.97 per 5-point increase).