Key result
Storage of platelet concentrates at 20 degrees C for 72 hours resulted in a 15% loss of total cholesterol and 7-11% loss of total phospholipid, which does not explain functional abnormalities.
Why the study?
Does storage of platelet concentrates at 4 degrees C or 20 degrees C alter their lipid composition compared to freshly prepared concentrates?
Does storage of platelet concentrates at 4 degrees C or 20 degrees C alter their lipid composition compared to freshly prepared concentrates?
Storage of platelet concentrates at 20 degrees C leads to minor lipid losses, but these changes do not explain the functional abnormalities that develop during storage.
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Minor lipid losses during platelet storage do not explain functional decline; leaves open alternative mechanisms of the storage lesion.
Hamid et al. (1980) studied Platelet concentrates. Storage at 20 degrees C vs. Freshly prepared concentrates and storage at 4 degrees C was evaluated on Lipid constituents (total cholesterol and total phospholipid). Storage of platelet concentrates at 20 degrees C for 72 hours resulted in a 15% loss of total cholesterol and 7-11% loss of total phospholipid, which does not explain functional abnormalities.
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