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January 1, 2001Experimental Biology and Medicine

VLCD-Induced Weight Loss Improves Heart Rate Variability in Moderately Obese Japanese

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Key result

Weight reduction of 17.8% using a very-low-calorie diet improved heart rate variability in obese patients, increasing the mean normal R-R interval and high-frequency component.

Why the study?

Does very-low-calorie diet-induced weight loss improve heart rate variability in moderately obese Japanese patients?

Population

16 moderately obese Japanese patients

Comparison

Very-low-calorie conventional Japanese diet… vs Pre-intervention baseline

Design

Cohort

Authors

YAYuko AkehiKoga HospitalHYHironobu YoshimatsuKyushu UniversityMKMamoru KurokawaNagasaki University

Discussion

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Overview

May support autonomic benefits of substantial weight loss in obesity; leaves open need for randomized outcome trials.

Study Design

Type

Observational (n=16)

Structured PICO

Does very-low-calorie diet-induced weight loss improve heart rate variability in moderately obese Japanese patients?

P
Population
16 moderately obese Japanese patients evaluated for heart rate variability before and after weight reduction via a very-low-calorie diet.
I
Intervention
Very-low-calorie conventional Japanese diet (VLCD-CJ) therapy combined with behavior therapy
C
Comparator
Pre-intervention baseline
O
Outcome
Heart rate variability (HRV) based on 24-hr ambulatory ECG recordingssurrogate

Significant weight loss achieved through a very-low-calorie diet improves autonomic nervous system function, particularly nocturnal heart rate variability, in moderately obese patients.

Cite This Study

Akehi et al. (2001) conducted an observational in Obesity (n=16). Very-low-calorie conventional Japanese diet (VLCD-CJ) and behavior therapy vs. Baseline (pre-weight reduction) was evaluated on Heart rate variability (HRV) based on 24-hr ambulatory ECG recordings. Weight reduction of 17.8% using a very-low-calorie diet improved heart rate variability in obese patients, increasing the mean normal R-R interval and high-frequency component.

synapsesocial.com/papers/6a23cd0dfdd7df511fd31e38https://doi.org/10.1177/153537020122600508
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac autonomic dysfunction in obese subjects1989 · 109 citations
  2. 2Obesity and cardiac function.1981 · 397 citations
  3. 3Noninvasive study of left ventricular performance in obese patients: influence of duration of obesity.1985 · 109 citations
  4. 4Autonomic nervous system activity in weight gain and weight loss1995 · 222 citations
  5. 5Postprandial Sympatho-Adrenal Activity: Its Relation to Metabolic and Cardiovascular Events and to Changes in Meal Frequency1995 · 50 citations