What does this research mean for the field?

Triple-negative and Luminal B breast cancer subtypes, along with PR status, Ki-67 expression, and histological grading, independently predict a higher risk of recurrence and metastasis in patients treated with radiotherapy. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to analyze the clinicopathological characteristics of breast cancer patients with varying genotypes who underwent radiotherapy and their impact on recurrence risk.

October 1, 2024International Journal of Radiation ResearchOpen Access

Clinicopathological characteristics of breast cancer patients underwent radiotherapy with different genotypes in relation to the risk of recurrence

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This study aims to analyze the clinicopathological characteristics of breast cancer patients with varying genotypes who underwent radiotherapy and their impact on recurrence risk.
Conducted a retrospective analysis on 256 breast cancer patients
Data included tumor grading, receptor status (ER, PR, HER2), and Ki-67 levels
Employed multifactorial analysis to assess relationships between characteristics
70.9% patients in low-risk, 23.2% in medium-high, and 5.6% in high-risk groups
PR, Ki-67, and histological grading were significant independent predictors of recurrence risk (P < 0.05)
Triple negative and Luminal B breast cancer patients showed higher metastatic risk (P < 0.05)

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Implication

Retrospective analysis finds correlations between pathology and recurrence risk in breast cancer variants.

Cite This Study

Ma et al. (2024) studied this question.

synapsesocial.com/papers/6a23da4e003b3cd7fea61ae8 https://doi.org/10.61186/ijrr.22.4.1043

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Clinicopathological characteristics of breast cancer patients underwent radiotherapy with different genotypes in relation to the risk of recurrence

Key Points

Discussion

Implication

Cite This Study

Clinicopathological characteristics of breast cancer patients underwent radiotherapy with different genotypes in relation to the risk of recurrence

Key Points

Discussion

Implication

Cite This Study

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