Why the study?
Do HDL subclasses correlate with the severity and progression of coronary atherosclerosis in young male MI survivors?
Population
60 men who survived a myocardial infarction before age 45 and underwent two coronary angiographies 4-7 years…
Design
Cohort
Follow-up
4-7 years
Authors
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HDL2b levels may mark lower coronary atherosclerosis severity in normotriglyceridemic post-MI patients; leaves open causal role or therapeutic targeting.
Do HDL subclasses correlate with the severity and progression of coronary atherosclerosis in young male MI survivors?
The largest HDL particles (HDL2b) are strongly inversely correlated with coronary atherosclerosis severity and progression, but this protective association is absent in hypertriglyceridemic patients.
Johansson et al. (1991) studied this question.
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