Why the study?
Does alimentary lipemia enhance cholesteryl ester transfer from HDL to apo B-containing lipoproteins compared to the fasting state?
Population
7 normolipidemic subjects (plasma samples)
Comparison
Alimentary lipemia (postprandial state) vs Fasting state
Design
Preclinical
Authors
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May promote CETP-mediated remodeling in lipemia; leaves open its role in human postprandial risk.
Does alimentary lipemia enhance cholesteryl ester transfer from HDL to apo B-containing lipoproteins compared to the fasting state?
Alimentary lipemia significantly enhances cholesteryl ester transfer from HDL to apo B-containing lipoproteins through multiple mechanisms including CETP redistribution and increased activity.
Tall et al. (1986) studied this question.
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