Why the study?
Does hydralazine, isosorbide dinitrate, or their combination improve central and regional hemodynamics in patients with low-output congestive heart failure?
Population
15 patients with low-output congestive heart failure
Comparison
Oral administration of 75 mg of hydralazine, 20… vs Baseline and comparative effects between the drugs
Design
Other
Authors
Loading...
Hydralazine may augment regional perfusion in low-output HF; leaves open outcome benefits and needs randomized confirmation.
Does hydralazine, isosorbide dinitrate, or their combination improve central and regional hemodynamics in patients with low-output congestive heart failure?
Hydralazine, but not isosorbide dinitrate, significantly increases renal and limb blood flow in proportion to augmented cardiac output in low-output congestive heart failure.
Leier et al. (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: