Population
Acutely isolated guinea-pig ventricular myocytes
Comparison
Alpha-adrenergic receptor activation with… vs Control conditions, or presence of antagonists
Design
Preclinical
Authors
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Alpha1-adrenergic PKC effects on Na-K pump current in myocytes require in vivo confirmation; leaves open relevance to human cardiac electrophysiology.
Alpha1-adrenergic receptor activation by noradrenaline increases Na+-K+ pump current in ventricular myocytes via a protein kinase C-dependent pathway.
Wang et al. (1998) studied this question.
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