June 19, 2003European Journal of Clinical Investigation

Impaired cardiovagal and vasomotor responses to baroreceptor stimulation in type II diabetes mellitus

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Why the study?

Are cardiovagal and vasomotor responses to baroreceptor stimulation impaired in patients with type II diabetes mellitus compared to healthy controls?

Structured PICO

Are cardiovagal and vasomotor responses to baroreceptor stimulation impaired in patients with type II diabetes mellitus compared to healthy controls?

Population

32 participants: 14 type II diabetic patients (age 57 +/- 7 years) and 18 healthy controls (age 59 +/- 11 years).

Intervention

Oscillatory neck suction at 0.1 Hz and 0.2 Hz with paced breathing at 0.25 Hz

Comparator

Healthy controls receiving the same stimulation

Outcome

Oscillatory responses of RR-interval and blood pressure evaluated by spectral analysissurrogate

Type II diabetes mellitus is associated with impaired baroreflex-mediated sympathetic modulation of blood vessels in addition to cardiovagal dysfunction.

Discussion

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Implication

Impaired baroreflex responses may indicate autonomic dysfunction in type 2 diabetes; hypothesis-generating for prospective validation.

Cite This Study

Sanya et al. (2003) studied this question.

synapsesocial.com/papers/6a23ffc99ed8aa0626a07f9d https://doi.org/10.1046/j.1365-2362.2003.01170.x

View Full Paper

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Impaired cardiovagal and vasomotor responses to baroreceptor stimulation in type II diabetes mellitus

Structured PICO

Discussion

Implication

Cite This Study

Impaired cardiovagal and vasomotor responses to baroreceptor stimulation in type II diabetes mellitus

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider