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December 1, 2024JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACYOpen Access

Medication cognitive burden tools largely lack clinical cutoffs, with ~82% focusing solely on anticholinergics.

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Why the study?

Multiple tools exist to help identify cognitive-impairing medications, yet a comprehensive description of these tools has not been undertaken.

Population

11 tools to assess the cognitive burden of a medication regimen

Design

Systematic review

Key result

A systematic review identified 11 tools to assess medication cognitive burden, of which 82% focused solely on anticholinergics and only one provided a clinical cutoff and alternative recommendations.

Authors

JSJacob StantonMGMichael R. GionfriddoGRGail B. Rattinger

Discussion

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Overview

Most cognitive-burden tools limit scope to anticholinergics and lack cutoffs; challenges current instruments and extends need for comprehensive pharmacist tools.

Study Design

Type

Systematic Review (n=11)

Structured PICO

P
Population
Systematic review of 11 tools designed to assess the cognitive burden of medication regimens.
O
Outcome
Identification and description of tools to assess cognitive burden from medications

Existing tools for identifying cognitive-impairing medications are largely outdated or limited to anticholinergics, highlighting the need for more comprehensive and implementable tools for clinical pharmacists.

Limitations

  • Many tools are limited by their development date
  • Focus primarily on anticholinergic medications
  • Lack clinically useful information
  • Many tools are limited by the development date
  • Focus on anticholinergic medications

Cite This Study

Stanton et al. (2024) conducted a systematic review in Drug-induced cognitive impairment (n=11). Tools to assess cognitive burden of medications was evaluated on Characteristics of tools to assess cognitive burden. A systematic review identified 11 tools to assess medication cognitive burden, of which 82% focused solely on anticholinergics and only one provided a clinical cutoff and alternative recommendations.

synapsesocial.com/papers/6a2415a89932235ca6bf4fc9https://doi.org/10.1002/jac5.2049
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Also Consider

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