What question did this study set out to answer?

To examine blood pressure and prolactin responses to bromocriptine in genetically hypertensive and normotensive rats.

January 1, 1989Clinical and Experimental Pharmacology and Physiology

Blood Pressure, Plasma and Pituitary Prolactin Responses to Bromocriptine in New Zealand Genetically Hypertensive and Normotensive Rats

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Authors

BTB.K.H. TanGuizhou University JHJ. S. HutchinsonAugusta University

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Implication

Randomized trial investigates bromocriptine effects on blood pressure and prolactin in hypertensive rats, suggesting a role in hypertension pathogenesis.

Key Points

To examine blood pressure and prolactin responses to bromocriptine in genetically hypertensive and normotensive rats.
Intraperitoneal infusion of bromocriptine delivered by osmotic minipump for 13 days.
Comparison of blood pressure and prolactin levels in genetically hypertensive and normotensive rats.
Vehicle-treated groups served as controls for comparisons.
Blood pressure significantly decreased in bromocriptine-treated genetically hypertensive rats compared to controls (p<0.05).
Mean plasma prolactin was significantly lower in bromocriptine-treated genetically hypertensive rats (p<0.05).
Greater suppression of pituitary prolactin content in bromocriptine-treated genetically hypertensive rats than normotensive rats.

Cite This Study

Tan et al. (1989) studied this question.

synapsesocial.com/papers/6a241e58637bef72baab3d07 https://doi.org/10.1111/j.1440-1681.1989.tb01903.x

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Implication

Randomized trial investigates bromocriptine effects on blood pressure and prolactin in hypertensive rats, suggesting a role in hypertension pathogenesis.

Blood Pressure, Plasma and Pituitary Prolactin Responses to Bromocriptine in New Zealand Genetically Hypertensive and Normotensive Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

Blood Pressure, Plasma and Pituitary Prolactin Responses to Bromocriptine in New Zealand Genetically Hypertensive and Normotensive Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

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