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Aspirin resistance is a clinical phenomenon with various definitions and etiologies, and current management strategies like dosing alteration or other antiplatelet agents have limited efficacy and safety.
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Aspirin resistance is a clinically significant phenomenon with multiple etiologies, but current management strategies remain limited in efficacy and safety.
The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety.
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Mansour et al. (2009) conducted a review in Aspirin resistance. Aspirin was evaluated. Aspirin resistance is a clinical phenomenon with various definitions and etiologies, and current management strategies like dosing alteration or other antiplatelet agents have limited efficacy and safety.
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