Key result
Annual CAC progression of ≥300 units is linked to an almost ~4-fold increase in CHD risk.
Why the study?
Does progression of coronary artery calcium predict future total and hard coronary heart disease events in adults aged 45-84 years?
Cohort (n=6,778)
Yes
Does progression of coronary artery calcium predict future total and hard coronary heart disease events in adults aged 45-84 years?
Hazard Ratio: 3.8 (95% CI 1.5–9.6)
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Progression of coronary artery calcium is a strong, independent predictor of future total and hard coronary heart disease events, particularly in patients with pre-existing CAC.
Budoff et al. (2013) conducted a cohort in Coronary heart disease (n=6,778). Progression of coronary artery calcium vs. No progression of coronary artery calcium was evaluated on Total coronary heart disease events (HR 3.8, 95% CI 1.5-9.6). Annual progression of coronary artery calcium of ≥300 units was associated with a significantly increased risk of total CHD events (HR 3.8; 95% CI 1.5-9.6) compared to no progression.
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