Key result
Myocardial ischaemia exhibits a circadian distribution with a morning peak and nocturnal trough, though specific triggers often remain unidentifiable and prediction elusive.
This review highlights the circadian distribution of myocardial ischemia and the ongoing challenge of identifying specific triggers for coronary events.
Alerts clinicians to morning ischaemia vulnerability; leaves open specific trigger identification for prediction.
The non-uniform occurrence of myocardial ischaemia, with a trough at night and a peak in the morning, is at the base of the concept of a circadian distribution of coronary events. Cardiovascular variables known to influence the occurrence of ischaemia have similar rhythms, and a likely culprit could be hidden among them. Nevertheless, in many cases an identifiable trigger is lacking and the prediction of ischaemia is still elusive.
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Gnecchi‐Ruscone et al. (1995) conducted a review in Myocardial ischaemia. Circadian rhythms was evaluated. Myocardial ischaemia exhibits a circadian distribution with a morning peak and nocturnal trough, though specific triggers often remain unidentifiable and prediction elusive.
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