Key result
Higher left atrial emptying fraction measured during atrial fibrillation independently predicts the maintenance of sinus rhythm 12 months after direct current cardioversion (OR 1.053).
Why the study?
Most studies evaluating echocardiographic predictors of maintaining sinus rhythm after DCCV for persistent AF have focused on parameters obtained during sinus rhythm rather than before DCCV.
Does left atrial emptying fraction (LAEF) measured during atrial fibrillation predict maintenance of sinus rhythm at 12 months after direct current cardioversion in patients with persistent AF?
Cohort (n=146)
No
Does left atrial emptying fraction (LAEF) measured during atrial fibrillation predict maintenance of sinus rhythm at 12 months after direct current cardioversion in patients with persistent AF?
Odds Ratio: 1.053 (95% CI 1.011–1.096)
Absolute Event Rate: 30.8% vs 24.6%
p-value: p=0.013
Left atrial emptying fraction measured during atrial fibrillation prior to cardioversion is an independent predictor of long-term sinus rhythm maintenance, suggesting mechanical remodeling parameters are superior to structural ones for this prognosis.
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LAEF during AF may aid post-DCCV risk stratification; extends observational data but leaves open any role in patient selection.
Wałek et al. (2020) conducted a cohort in Persistent atrial fibrillation (n=146). Left atrial emptying fraction (LAEF) vs. Lower LAEF / AF recurrence group was evaluated on Sinus rhythm maintenance at 12 months (OR 1.053, 95% CI 1.011-1.096, p=0.013). Higher left atrial emptying fraction measured during atrial fibrillation independently predicts the maintenance of sinus rhythm 12 months after direct current cardioversion (OR 1.053).
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